Understanding the molecular basis of quantitative variation has the potential of explaining numerous phenotypes, including common human diseases such as asthma, atherosclerosis, diabetes, hypertension, and obesity. The goal of QTL (Quantitative Trait Loci) mapping is to identify and characterize the DNA sequences responsible for these conditions. Although it has been very difficult to conduct linkage studies in humans, QTL have been mapped in inbred species: rodents, insects and plants. Despite this progress, finding the genes underlying quantitative traits remains a challenge.
QTL MATCHMAKER is a tool which addresses this problem.
It allows for high throughput mapping of genes to known QTL and comparative
genomics analysis between Homo sapiens, Mus musculus, Rattus norvegicus.
The QTL database organizes information, which are scattered through
numerous web sites and publications.
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QTL MATCHMAKER is provided by Bottinger Lab, MSSM.
© 2004 MSSM. All Rights Reserved.
Compiled from a number of public databases.
Data are curated from MGD , RatMap , RGD , PubMed , OMIM ,and UCSC Genome Browser .
Powered by LIMS team @ Mount Sinai School of Medicine, 2004